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Lioresal

Lioresal

Availability: In stock

$0.89

Generally Baclofen is indicated to reduce and relieve the excessive stiffness to improve patient’s mobility, making for greater independence in accordance to an ongoing passive and active physiotherapy. Patients should be given a trail dose and after that medication should be consider for long term. It is specifically indicated for suppression of voluntary muscle spasm in: Multiple sclerosis and Spinal lesions of traumatic, infectious, degenerative, neoplastic and unknown origin, causing: skeletal hypertonus and spastic and dyssynergic bladder dysfunction. Not recommended in Parkinson's disease or spasticity arising from strokes, cerebral palsy or rheumatoid disorders. Patients suffering from psychotic disorders, schizophrenia, depressive or manic disorders or confusional states should be treated cautiously only under careful surveillance. Baclofen has not been approved by the FDA for oral use in children under twelve.

Quantity Strength Unit Price Price Cart
30 Tablets Lioresal 10mg $0.90 $26.99
90 Tablets Lioresal 10mg $0.89 $79.99

Details

LIORESAL (Generic name Baclofen) is a muscle relaxant used to manage muscle spasticity in patients. It is a derivative of gamma-aminobutyric acid (GABA) with chemical name 4- amino- 3-(4- chlorophenyl) butanoic acid. The non-medicinal ingredients present in a Lioresal dose are microcrystalline cellulose, cornstarch, magnesium stearate and povidone. It is an effective anti-spastic agent with a spinal site of action. Baclofen also has central sites of action given the adverse event profile and general CNS depressant properties. It mimics γ-aminobutyric acid (GABA) within the spinal cord and works by depressing monosynaptic and polysynaptic afferent reflex activity at the spinal cord level, thereby reducing skeletal muscle spasm caused by upper motor neuron lesions. In neurological diseases associated with spasm of the skeletal muscles, theclinical effects of Lioresal take the form of a beneficial action on reflex muscle contractions and of marked relief from painful spasm, automatism and clonus. Baclofen was approved by the FDA in November 1977.

What to do in case of overdose?

If someone has taken overdose of Lioresal, he should immediately consult to healthcare provider. Haemodialysis effectively removes baclofen from the body, alleviates clinical symptoms of overdose and shortens the recovery time in these patients. The main symptoms of overdose are drowsiness, breathing difficulties, trouble of consciousness, blurred vision, unusual muscle weakness, and sudden contraction of the muscles, poor or absent reflexes, high or low blood pressure, slow, fast or irregular heartbeat, nausea and vomiting.

Do children can take this medication?

No, Lioresal medication is not recommended for children.

What if I stop medication suddenly?

Any medication should only be stop under observation of your doctor as sudden change may cause adverse effect on your treatment. In case of Lioresal, this are some symptoms that may occur if you suddenly stop treatment: nervousness, abnormal thinking or behaviour, uncontrollable twitching, jerking or writhing movements, fast heart beat, high body temperature. More upon it the excessive stiffness (spasms) in your muscles may also worsen.

What are other uses of baclofen?

Baclofen is an approved treatment for alcoholism and further clinical trials are going on for treatment of autism also.

How do I know which muscle relaxant is best for me?

All drugs have some benefits and some risks so it is on your doctor to decide which medication will be worth for you depending upon your all medical history and current condition. Each person reacts differently to any medication. May be your doctor will give you a trial dose to know effectiveness of the drug.

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Additional Information

Generic BACLOFEN (BAK loe fen)
Strength Lioresal - BACLOFEN 10mg
Dosage Treatment should always be initiated with small, gradually increasing doses of Lioresal. It should be taken during meals with a little liquid. Treatment usually starts with 15 mg daily, preferably taken in divided doses. The dose is then gradually increased until the best results are obtained. In order to prevent excessive weakness and falling, Lioresal should be used with caution when spasticity is needed to sustain upright posture and balance in locomotion or whenever spasticity is used to maintain function. Do not exceed the recommended dose. In case of missing a dose, take the dose as you remember but maintain a minimum gap of 6 hour with your next dose. Do not use extra medicine to make up for a missed dose. If you do not want to continue medication further please consult your doctor as abrupt or sudden stop can cause side effects. You may need to slowly decrease your dose before stopping it completely. Store below 25 degrees C in a closed container, away from heat, moisture, and direct light. Medicines should be kept out of the reach of children.
Side Effects It has been observed Lioresal medication causes some mild side effects like nausea and sleepiness in most of the cases which are subsided after a few days of treatment. Particular caution is required when combining Lioresal to drugs or medicinal products thatcan significantly impact renal function. Renal function shall be closely monitored and Lioresal daily dosage adjusted accordingly to prevent baclofen toxicity. Other than this if you experience over sweating, frequent urination, constipation and diarrhea, pain in muscle or any other symptom that is bothering you, it is better to call an appointment with your doctor.
Precaution Before starting any medication it is always better to talk to your doctor or pharmacist about your medical history. If you have any of the following symptoms please take this medication only after proper consultation: • Peptic ulcers or with a history of peptic ulcers • Cerebrovascular diseases or respiratory or hepatic insufficiency • Diabetes mellitus (baclofen may increase blood glucose concentrations) • Have kidney disease. • Hypertension • Older people (aged 65 years or above) or people with a disturbance of circulation in the brain • Though there are no adequate proofs for baclofen effects in pregnant women yet it should not be taken if you are pregnant or breastfeeding unless the potential benefit outweighs the potential risk to the fetus or new born. • Alcoholic Other than above Baclofen may be associated with dizziness, sedation, somnolence and visual disturbance which may impair the patient’s reaction. If this happens to you, do not drive a car, use a machine, or do other things that need your full attention.

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