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Generic Epivir or Lamivudine is used for treatment of infection that occurs due to hepatitis B and HIV. It belongs to the class of drug known as nucleotide reverse transcriptase inhibitor. This medicine does not cure HIV and also does not work in preventing spread of HIV to other person via blood transfusion, sexual contact, etc. Generic Epivir works by decreasing the amount of HIV and hepatitis B in the blood. It also decreases the chances of developing AIDS (Acquired Immunodeficiency Syndrome). The patient should take proper care of themselves so as to avoid its spread or transmission to others.
Quantity Strength Unit Price Price Cart
30 Tablets Epivir 100mg $1.07 $31.99
90 Tablets Epivir 100mg $1.07 $95.99
30 Tablets Epivir 150mg $1.67 $49.99
90 Tablets Epivir 150mg $1.64 $147.99


Generic Epivir is group of medicine that is known as reverse transcriptase inhibitors. This medicine is manufactured by various pharmaceutical located at various geographical location and available under different trade names such as Zeffix, Heptovir, Epivir-HBV
Generic Epivir is used to treat chronic Hepatitis B at lower dose. In addition, it is used to treat HIV infection and hepatitis B infection. This effective medicine improves seroconversionof e-antigen positive hepatitis B and improves histology stages of liver. Its long term use provides resistivity to virus that causes hepatitis of mutant brand. Generic Epivir has approval from FDA in the year 1995.

During HIV infection, the virus that causes HIV gets multiply inside cells of the body. These viruses are then release from the cells and get spread in the body where they infect other cells. Therefore, HIV infection gets spread to new and uninfected cells that is produced in the cells. When new HIV virus is produced in the body, then this should manufacture new DNA for each virus. The enzyme, reverse transcriptase is the enzyme that is known to form new DNA. Lamivudine is converted in its active form, lamivudine triphosphate inside the body. This active form is similar in function as deoxycytidine triphosphate that is utilized by reverse transcriptase for new DNA formation. The enzyme, reverse transcriptase uses lamivudine triphosphate instead of Deoxycytidine triphosphate and interferes with its action.

Generic Epivir should be stored at room temperature and it should be protected from light and moisture. The patient should check the expiry date of the medicine before taking it.

Generic Epivir is synthetic nucleotide that works against HIV-1 and HBV. Chemically, lamivudine is known as (2R,cis)-4- amino-l-(2-hydroxymethyl-l,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one. It has a molecular weight of 229.3 and molecular formula as C8H11N3O3S. It is white to off-white crystalline solid. The film-coated tablet of generic Epivir contains various inactive ingredients such as magnesium stearate, hypromellose, microcrystalline cellulose, polysorbate 80, sodium starch glycolate, titanium dioxide, etc.

Other medicine of same class includes:

• Zalcitabine (Hivid)
• Zidovudine (Retrovir)
• Didanosine (Videx)
• Emtricitabine (Emtriva)
• Stavudine (Zerit)

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Additional Information

Generic LAMIVUDINE-(la mi vyoo deen)
Strength Epivir - LAMIVUDINE 100mg

For treating HIV infection, the adult patient should be given 150 mg of generic Epivir twice daily or 300 mg once in a day.

The patient with weight 50 kg should be given 4 mg per kg of generic Epivir two times in a day.

The dose for neonates should be 2 mg per kg of generic Epivir twice in a day.

Adult patient suffering from hepatitis B infection should be given generic Epivir of 100 mg daily.

Side Effects

Some of the side effects experienced by the patient include pancreatitis, liver failure and lactic acidosis. This results in decrease in blood cells, pain in muscle, weakness, peripheral neuropathy (nerve damage in extremities).Some of the symptoms of peripheral neuropathy are tingling, numbness and pain in feet and hands.

Some patient might suffer from abdominal pain, fever, nausea, vomiting, diarrhoea, weight loss and hair loss.

Few patients might experience headache, dizziness and trouble in sleeping.

Sometimes, the user of generic Epivir also suffer from anaemia, depression, increase in fat content in upper back, stomach area, decrease in fat in arm and leg.

Some patients might get allergic reactions after intake of generic Epivir such as rash, swelling in throat, tongue, face, severe dizziness and trouble in breathing.


If the patient is allergic to any medicine then, they should tell to the doctor before taking Epivir.

In case, the user of generic Epivir has any medical record of kidney problem, pancreatitis, liver problem, then they should explain to the doctor before taking the medicine.

Intake of alcohol or alcoholic beverages should be avoided by the patient while taking generic Epivir as it might increase the chance of liver or pancreas problem.

Generic Epivir makes the patient feel dizzy, therefore, work that requires alert should be avoided by the patient.

In case of using herbal product, prescription or non-prescription drugs, the patient should tell to the doctor before taking the generic Epivir.

To reduce the chances of spreading HIV infection, the patient should take proper precautionary steps themselves.

Pregnant patient should consult to the doctor before taking generic Epivir. They should discuss with the doctor the risk and benefit of taking this medicine.

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