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Combivir

Combivir

Availability: In stock

$3.50

Generic Combivir is a combination of 2 drugs namely lamivudine and zidovudine and belongs to the class of drug known as nucleotide reverse transcriptase inhibitors. This is used for controlling HIV infection and thus improves quality of life. During HIV infection, immune system weakens. Generic Combivir functions by decreasing the number of HIV in the body so that the immune system can function properly. In addition, generic Combivir also works by lowering the chances of complication that might arise due to HIV disease.

Generic Combivir do not prevent the spread of HIV to other. Instead it helps in preventing HIV infection after contact with the virus.


Other medicines of same category are:


• Zalcitabine (Hivid)
• Emtricitabine (Emtrivir)
• Didanosine (Videx)

Quantity Strength Unit Price Price Cart
30 Tablets Combivir [Lamivudine 150mg + Zidovudine 300mg] $3.73 $111.99
90 Tablets Combivir [Lamivudine 150mg + Zidovudine 300mg] $3.50 $314.99

Details

Combivir is an oral drug that belongs to the class of drug known as reverse transcriptase inhibitors. It is a combination of two drugs; lamivudine (Epivir) and zidovudine (Retrovir). Generic Combivir is used for treating infections caused due to human immunodeficiency virus (HIV).

During HIV infection, the HIV virus multiples inside the cells of the body and this newly formed viruses are released from the cells and get spread in the whole body and infect other cells. Therefore, the infections spread to all the uninfected cells of the body. It is very important for HIV virus to manufacture new DNA for each virus. This is done by the enzyme reverse transcriptase that is responsible for formation of new DNA and virus uses this. Both lamivudine and zidovudine blocks the activity of reverse transcriptase and therefore production of new DNA and virus is blocked. Deoxycytidine triphosphate and thymidine triphosphate is responsible for production of new DNA. Lamivudine is converted to its active form lamivudine triphosphate and zidovudine is converted to zidovudine triphosphate and is used by reverse transcriptase for the formation of DNA instead of naturally occurring chemicals. It is this active form that is known to interfere the activity of reverse transcriptase.

When lamivudine or zidovudine is used separately, it shows less effect. On the other hand, when both is used as Combivir, it become tough for the HIV virus to develop the resistance to the therapy. Generic Combivir was approved by FDA in September 1997.

Generic Combivir is stored at a temperature that ranges from 2-30 degree centigrade, away from light and moisture. It is kept at a place that is safe from child and pet.

Generic Combivir contain lamivudine 150 mg and zidovudine 300 mg. This film-coated tablet contains various inactive ingredients such as colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, polyethylene glycol, polysorbate 80 and titanium dioxide.

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Additional Information

Generic Lamivudine & Zidovudine(zye-DOE-vue-deen & la-MI-vue-deen)
Strength Combivir [Lamivudine 150mg + Zidovudine 300mg]
Dosage One tablet of generic Combivir is taken as oral dose twice in day for 30 kg and above weight. This is not essential to take this generic Combivir without food.
Side Effects

Some of the serious side effects of Combivir includes decrease in the blood cells, muscle pain, pancreatitis, liver enlargement, fatty liver, lactic acidosis and hypersensitivity reactions.

In addition, the user of generic Combivir can also suffer from chill, rash, abdominal pain, nausea, vomiting, weight loss, cough, insomnia and accumulation or redistribution of fat.

Few users of generic Combivir might suffer from headache, tiredness, loss of appetite, diarrhoea, trouble in sleeping, stuffy nose and dizziness.

Furthermore, some patients might also experience continuous weight loss, persistent muscle aches, weakness, joint pain, numbness, tingling of the hands & feet, non-healing skin sores, cough, chills, fever, irritation, nervousness, heat intolerance, bulging eyes, slurred speech, paralysis, etc.

Precaution

If the patient is allergic to lamivudine or zidovudine or any of the inactive ingredients present in the generic Combivir, then they should to the doctor before taking this medicine.

In case, the user of generic Combivir has any medical history related to liver, kidney such as hepatitis B or C, cirrhosis, problem related to pancreas (pancreatitis), low count of blood cells (white/red), then the patient should explain to the doctor prior using medicine.

Intake of alcoholic beverages should be limited during the treatment with generic Combivir as it can increase the chances of liver and pancreas problem. It makes the user feel dizzy so work that that requires alertness should be avoided by the patient.

If the user of generic Combivir is using any prescription, non-prescription or herbal products then they should reveal to the doctor before starting the treatment.

For reducing the chance of HIV disease getting spread from one person to other, the affected person should use some effective barrier method.

This medicine might pass to the breast milk and can transmit HIV to the infant. Therefore, breast-feeding patient should consult to the doctor and discuss about all the risks and benefits of taking generic Combivir.

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