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Buy Avana 100 MG

Buy Avana 100 MG

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Avanafil is the latest medicine used for erectile dysfunction. It is exceptional among other erectile dysfunction medicines because of its safety and efficacy. Avanafil does not produce vision related problems which is very frequent side effect of other Phosphodiesterase 5 (PDE-5) inhibitors.

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10 Pills 100 $3.95 $39.50
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Avanafil is a novel drug which belongs to the class of medicines known as “Phosphodiesterase type 5 (PDE5) inhibitors”. It was approved in 2012 by FDA (food and drug administration) and in 2013 by EMA (European medicine agency). Avanafil is employed in men for the treating Erectile Dysfunction. It is highly selective towards PDE-5 than other Phosphodiesterase inhibitors. It acts faster than other medicines used for erectile dysfunctions with an onset of action in 30–45 minutes. It does not show side effects related to vision and QTc interval.

What is the mechanism of action of Avanafil?  

Avanafil is a Phosphodiesterase enzyme inhibitor having 100 times more selectivity for Phosphodiesterase type 5 (PDE-5) in comparison to other Phosphodiesterase types. Phosphodiesterase type 5 (PDE-5) is an enzyme which destroys cGMP in the penile tissue (corpus cavernosum). During sexual stimulation, nerve endings and endothelial cells release nitric oxide which starts the production of cGMP in smooth muscles of the penis. cGMP is a chemical substance which widens blood vessels of penis and augment the penile blood flow; this causes  erection of penis. Avanafil boost up the concentration of cGMP by blocking Phosphodiesterase -5.

What are the indicated uses of Avanafil?

Avanafil is used for treating erectile dysfunction in men. It is acts promptly as compared to other Phosphodiesterase inhibitors.

What are the doses of Avanafil?

The dose of Avanafil can vary from 50 mg to 200 mg in different individuals depending upon the age, tolerability and concomitant illness of the patients. This medicine is meant to be administering orally with or without food but always avoid fat rich diet. It starts acting in 30 minutes so take it 30 minutes before love making. Never exceed a total dose of 200 mg in a day. Two doses of Avanafil should not be taken within a period of 24 hours.

What to do in case of missing a dose?

This medicine is intended to be taken only preceding physical intercourse so likelihood of missing the dose does not exist.

What are the side effects associated with Avanafil?

Avanafil is a safe drug but some side effects like headache, blocked nose, flushing, back pain and light-headedness can occur. These are not serious but if they remain for a long time or intensify then consult your doctor immediately.

Some serious side effects are seen in few males (less than 1%) taking Avanafil. These are:

  1. Whole body — fatigue, swelling of hands and/or feet

  2. Musculoskeletal system— musculoskeletal pain, spasms of muscles              

  3. Cardiovascular system — chest pain (angina), palpitation

  4. Digestive system — diarrhoea, change in blood glucose levels, vomiting

  5. Skin – redness, itching, blisters, irritation

  6. Urinary system– blood in urine, infection of urinary tract

  7. Reproductive system- Priapism (painful erection which lasts for more than 4 hours)

  8.        Nervous system — insomnia

    1. Respiratory system — cough, troubled breathing, epistaxis (bleeding from nose)

What are the contraindications with the use of Avanafil?

  1. Nitrate containing medicines never be used with Avanafil because it can lead fainting due to lowering of blood pressure.

  2. Individuals who are hypersensitive to Avanafil or any other PDE-5 inhibitor should not use Avanafil.

  3. Avanafil is contraindicated in women and boys below 18 years of age.

  4. Limit the alcohol consumption with Avanafil or any other PDE5 inhibitors because it can cause hypotension and diminish alertness.

What precautionary measures should be followed while using Avanafil?

  1. Make an avoidance to take nitrate therapy with Avanafil. If you require nitrates then consume them after at least 12 hours of taking Avanafil.

  2. Initiate with 50 mg of Avanafil, if you are taking alpha blockers concomitantly.

  3. Do not use other Phosphodiesterase inhibitors concomitantly with Avanafil.

What to do in case of over dosage with Avanafil?

In case you consumed a large amount of Avanafil (dose of 800 mg or more) seek immediate medical care.

What are the drug interactions with Avanafil?

Medicines that interact with Avanafil are:

  1. Nitrates like nitro glycerine, isosorbide dinitrate, isosorbide mononitrate and nitrites such as amyl nitrite

  2. Alpha-Blockers like terazosin, parazocin, doxazocin.

  3. Other Phosphodiesterase inhibitors (PDE-5) used for erectile dysfunction like sildenafil, tadalafil, verdenafil. 

  4. CYP3A4 Inhibitors such as telithromycin, ketoconazole, ritonavir, clarithromycin, Indinavir and nelfinavir.

  5. HIV medicines such as ritonavir, saquinavir.

  6. Medicines for hypertension like lisinopril, enalapril, felodipine.

Always discuss with your doctor before using a medicine while on therapy with Avanafil.

How to store Avanafil?

It should only be stored at room temperature (below 30 degree Celsius) away from sunlight in a cool place. Keep it out of the reach of children and pets. Do not use the medicine after the expiration date given on the label of medicine.

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Additional Information

Generic Avanafil 100mg Tablet
Strength 100
Dosage No
Side Effects No
Precaution No

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