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Advair Rotacaps

Advair Rotacaps

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What is Advair Diskus?

Advair Diskus is a combination preparation of Fluticasone propionate and salmeterol xinafoate, which is used for the management of respiratory disorder like asthma and chronic pulmonary obstructive disease. This therapy is very effective to control and prevent the symptoms like shortness of breath, wheezing sound, chest pain and helps keep maintaining a favourable lifestyle. Fluticasone propionate is a corticosteroids and Salmeterol xinafoate is long-acting beta agonist. In asthma and all the CPODs (chronic pulmonary obstructive disease), respiratory airways become constricted and inflamed. Because of this constriction and inflammation, the patient is not able to breathe out the air free and it causes to develop the symptoms. Advair Diskus or any respiratory medication should be used regularly to achieve an effective result. This drug is used in adult and the children between the ages of 4-6 years.

Quantity Strength Unit Price Price Cart
1 Cap Advair Rotacaps - 30 (Fluticasone & Salmeterol 100/50mcg) $63.00 $63.00
2 Cap Advair Rotacaps - 30 (Fluticasone & Salmeterol 100/50mcg) $63.00 $126.00
3 Cap Advair Rotacaps - 30 (Fluticasone & Salmeterol 250/50mcg) $63.00 $189.00


How does Advair Diskus work for you?

Advair Diskus is a preparation of Fluticasone propionate and salmeterol xinafoate, which fulfill both the requirement needed in the treatment of asthma and CPODs. The exact mechanism of action of this therapy is not known. But it assumed that when the patient suffering from these diseases start to take this combination therapy, Fluticasone propionate starts working on the constricted parts and salmeterol xinafoate starts working for the inflammation of the bronchioles starting from the trachea to the terminal bronchioles. Thus the symptoms come under control and helps keep maintain a comfortable breathing. Advair Diskus works by activation of the beta adrenergic receptors of the bronchial smooth muscles of the lung which further cause the activation of the cyclase adenylate monophosphate. The activated cyclase adenylate monophosphate stimulates the activation of the protein Kinase-A which pause the phosphorylation of myosin. When the myosin phosphorylation stops, it lowers the intracellular ionic calcium level and improves the airway smooth muscle relaxation.

 What are the indications of Advair Diskus?

Advair Diskus is used in the patients who are suffering from asthma and chronic pulmonary obstructive diseases (CPODs) of lung like chronic bronchitis, emphysema or both.

Advair Diskus in asthma:

  1. This drug is used to control the symptoms of asthma like shortness of breath and wheezing sound in both the adult and children between the ages of 4-6 years.

Advair Diskus in CPODs:

  1. It is a prescription drug used for the treatment of some chronic diseases like emphysema, Chronic bronchitis etc. It keeps the symptoms of COPD under control for several days.

Always use this drug according to the instructions of your physician because this combination therapy is mainly created for the treatment of chronic respiratory problems. 

Doses of Advair Diskus:

It is available in three strengths such as:

  1. Advair Diskus 100/50(flutacasone propionate 100mcg and salmeterol 50mcg inhalation powder)

  2. Advair Diskus 250/50(Flutacasone propionate 250mcg and salmeterol 540mcg inhalation powder)

  3. Advair Diskus 500/50(Flutacasone propionate 500mcg and salmeterol 50mcg inhalation powder)

Always read carefully the leaflet that comes with the Advair Diskus before taking the medication. But the consultation with your doctor should always be the first priority to take the therapy. Because the health care provider only will decide whether you are fit for the therapy or not.

What are the contra-indications of Advair Diskus?

This combination therapy has the following contra-indications:

  1. It is not used in the patient who are allergic to protein milk. If you are sure, ask for your doctor.

  2. If you are allergic to Flutacasone, salmeterol or any other components of the preparation.

  3. Other conditions: This  preparation is not used in a patient who has the following problems,

Cardiac problems

  1. High blood pressure

  2. Thyroid problem

  3. Osteoporosis

  4. Low immunity

  5. Eye problems like glaucoma or cataract.

  6. If you have viral, bacterial or fungal infections.

  7. Children who are exposed to measles or chicken pox

  8. Patient who are allergic to any components of the preparations.

  9. Pregnancy and lactation period.

What is the drug Interaction of Advair Diskus?

  1. Always inform your doctor if you are taking any over-the-counter medicines, vitamins, herbal supplements because these drugs can interact with Advair Diskus and cause serious complications.

  2. Always avoid anti-fungal or anti-HIV medicines if you are going to use this medication.

  3. Do not forget to inform your physician if you are taking anti-hypertensives, anti-convulsants.

  4. Never use this medication if you are allergic to any of the components of the preparation.

What should you do if you miss dose?

By chance, if you miss a dose, skip the missed dose. Take the next dose according to the schedule. You should never take the 2 doses together.

What should you do if you take an overdose?

If you take Advai Diskus in extra amount, contact with your doctor or the emergency department of your nearest hospital if you catch the symptoms like shortness of breath, increased heart rat or shakiness.

What are the side effects of Advair Diskus?

Some of the side effects of this therapy are mentioned below:

  1. Fungal infection: Advair Diskus may cause fungal infection in your mouth. Always rinse your mouth with water after using this inhalation to reduce the chance of infections.

  2. Pneumonia: Patient suffering from CPOD are more prone to develop pneumonia during using this therapy and catch the following symptoms:

  3. Increased mucus production.

  4. Fever

  5. Cough

  6. Breathing problem

  7. Poor immunity

  8. Adrenal insufficiency:

  9. Feeling tired

  10. Weakness

  11. Nausea and vomitng

  12. Hypotension 

Allergic Reaction:

Always consult with your doctor if you catch the symptoms like:

  1. Edema or swelling of your face.

  2. Rashes on the skin.

  3. Difficulty in breathin.

Cardiac effect:

  1. High blood pressure

  2. Cardiac arrhythmias

  3. Chest pain

  4. Bone problem

Central nervous system effect:

  1. Anxiety

  2. Tremors

  3. Nervousness

Eye problem:

  1. Eye pain

  2. Glaucoma 

Steps of using Advair Diskus:

The following steps should be used if you are using this inhaler:

  1. Step1:Open the advair Diskus and hold it with the left hand. Then place your thumb of the right hand on the grip and push the thumb grip away from you till the mouthpiece is seen and placed into place.

  2. Step2: Slide the lever until a click sound is heard. Hold the Diskus in the proper position keeping the mouthpiece towards you. After that you should slide the lever away from mouthpiece till you hear the click sound. Then the counter will count down the number by 1 and now you can use the Diskus.

  3. Step3: Step3 is inhalation. Before you inhale, breath out deep when you hold the Diskus away from the mouth. You should not breath into the mouthpiece. Then put the mouthpiece to your lips and breath in and out quickly. While doing this, do not breath through the nose. Then take the mouthpiece away from the your mouth and hold your breath for 10 minutes. Diskus deliver the medication in powder form.

  4. Step4: Closing of Diskus.

Place your thumb on the thumb grip and slide the lever back till the click sound is heard and the mouthpiece is not visible.

Precautions and warnings of Advair Diskus:

You should take the following precautions while you are taking this medication:

  1. Always Inform your doctor if you are taking any LABA medicines.

  2. Do not stop using this medication without consulting with a health care provider because it may cause some complications.

  3. Always take advice from your doctor if you develop any side effects mentioned above.

Always keep a rescue inhaler if you are using this medication. Because Advair Diskus may not give sudden relief. 


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Additional Information

Generic Fluticasone (floo-TIK-a-sone) & Salmeterol (sal-ME-te-role)
Strength Advair Rotacaps - 30 (Fluticasone & Salmeterol 100/50mcg)
Dosage No
Side Effects No
Precaution No

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